Ned lived a happy life growing organic vegetables on a farm with his hippie girlfriend and his dog named Willie Nelson, but an unadvised incident with marijuana at a farmer's market lands him in jail. When he gets out of jail, he is off to live with his sisters. While Ned is still happy, his sisters are much less so after he manages to screw up one marriage, one job opportunity, one budding relationship and one domestic partnership. He sees those problems as breakdowns in communication, but his sisters see him as an idiot.

Cypress Hill were notable for being the first Latino hip-hop superstars, but they became notorious for their endorsement of marijuana, which actually isn't a trivial thing. Not only did the group campaign for its legalization, but their slow, rolling bass-and-drum loops pioneered a new, stoned funk that became extraordinary influential in '90s hip-hop — it could be heard in everything from Dr. Dre's G-funk to the chilly layers of English trip-hop. DJ Muggs crafted the sound, and B Real, with his pinched, nasal voice, was responsible for the rhetoric that made them famous. The pro-pot position became a little ridiculous over time, but there was no denying that the actual music had a strange, eerie power, particularly on the band's first two albums. Although B Real remained an effective lyricist and Muggs' musical skills did not diminish, the group's third album, Temples of Boom, was perceived by many critics as self-parodic, and the group appeared to disintegrate shortly afterward, though Muggs and B Real regrouped toward the end of the '90s to issue more material.

While being transported by two detectives in a car, the dangerous criminal Krug is rescued by his brother Francis and his girlfriend Sadie, and they brutally kill the detectives. Meanwhile Emma, her husband Dr. John and their seventeen year-old daughter Mari Collingwood head on vacation to their house nearby the lake. Mari borrows the family car to meet her friend Paige that is working in a store in the town. They befriend the teenager Justin in the store and he offers some marijuana to the pothead Paige in the motel where he is lodged.