Two years later, after Commander Shepard repel an invasion, the Reapers, a new enemy of mankind. On the outskirts of the habitable space one gradually destroys human colonies. To stop the imminent threat, Shepard to cooperate with a network of Cerberus a ruthless organization, which proclaims the survival of humanity at any cost. To fulfill this important mission Shepard must assemble a strong team and take command of the most powerful spaceship in the galaxy. But even with such resources, most consider it a hopeless venture. Commander Shepard to prove to skeptics that they were wrong.