Tired and irritable, Zakes Abbott drives home along the motorway, his girlfriend, Beth, asleep beside him. Failing to spot his exit he speeds across the causeway, cutting up a white van and barely avoiding an accident. Apoplectic with rage, the truck driver gives chase, and as he violently overtakes the tailgate flips up revealing a woman bound and bloodied in the back. But before there is time for a second look, the door is slammed shut and Zakes is left bewildered and wondering if what he saw was real. Later at a service station, Zakes' fears grow when Beth goes missing, and as he begins a frantic search, he is enticed into a deadly game of cat and mouse on the deserted motorway.